Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50091293' TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery Ltd.
Curated by ChEMBL
Argenta Discovery Ltd.
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Argenta Discovery Ltd.
Curated by ChEMBL
Argenta Discovery Ltd.
Curated by ChEMBL
Affinity DataEC50: 53nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
