Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK4' and Ligand = 'BDBM50044654'
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
EntreMed Inc.

Curated by ChEMBL
LigandPNGBDBM50044654(CHEMBL3353346 | US9907800, Example A62)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human N-terminal GST-tagged PLK4 (1 to 391 residues) expressed in Escherichia coli incubated for 30 mins by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125V9WPubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
EntreMed Inc.

Curated by ChEMBL
LigandPNGBDBM50044654(CHEMBL3353346 | US9907800, Example A62)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent