Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Sgk1' and Ligand = 'BDBM50043018'
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM50043018(CHEMBL3355028 | US9718825, Example 63)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VM4F82US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM50043018(CHEMBL3355028 | US9718825, Example 63)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of SGK1 (unknown origin) assessed as substrate phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5BFBPubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM50043018(CHEMBL3355028 | US9718825, Example 63)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant SGK1 (unknown origin) expressed in U2OS cells by cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5BFBPubMed