Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50240973' TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataKi: 203nMAssay Description:Inhibition of human C-terminal GST-tagged mTOR (1360 to 2549 residues) expressed in baculovirus expression system using after 1 hr AlexaFluor647-labe...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataIC50: 312nMAssay Description:Inhibition of mTOR in human A2058 cells assessed as reduction in phosphorylation of S6 at ser235/236 residues after 1 hr by in-cell Western methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataKd: 61nMAssay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
