Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50315213'
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15439PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant mTOR using substrate PI incubated for 1 hr by Adapta kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1TPXPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of human mTOR by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MWRPubMed