Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50343759'
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50343759(1-ethyl-3-(4-(6-(2-hydroxypropan-2-yl)-4-morpholin...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C6XRHPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50343759(1-ethyl-3-(4-(6-(2-hydroxypropan-2-yl)-4-morpholin...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of human N-terminal FLAG-tagged mTOR (1362-end residues) in presence of [gamma33P]ATP after 40 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN692KPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50343759(1-ethyl-3-(4-(6-(2-hydroxypropan-2-yl)-4-morpholin...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125TSRPubMed