Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50401254'
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50401254(CHEMBL2206906 | US8772480, 335)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant N-terminal GST-tagged mTOR using GFP-4EBP as substrate after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50401254(CHEMBL2206906 | US8772480, 335)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123FJUS Patent