Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50468002'
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468002(CHEMBL4291436)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468002(CHEMBL4291436)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of mTOR in human MDA-MB-468 cells assessed as decrease in 70S6K S235/236 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50468002(CHEMBL4291436)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mTOR in human MDA-MB-468 cells assessed as decrease in AKT phosphorylation at S473 residueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VPQPubMed