Found 2 Enz. Inhib. hit(s) with Target = 'Serine palmitoyltransferase 1' and Ligand = 'BDBM50535848' 
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human SPT1 expressed in microsomes of HEK293 cells incubated for 1hr by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 977nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
