Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Serine protease hepsin' and Ligand = 'BDBM50063698'
TargetSerine protease hepsin(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Inhibition of recombinant hepsin (unknown origin) using Boc-QAR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4DV8PubMed
TargetSerine protease hepsin(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Inhibition of hepsin (unknown origin) using Boc-QAR-AMC as substrate after 30 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4RB4PubMed
TargetSerine protease hepsin(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VVTPubMed