Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM20273'
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
Yale University

LigandPNGBDBM20273((2S)-2-[(2S)-2-[(4-cyanophenyl)formamido]-3-[4-(ph...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+4nMpH: 7.8 T: 2°CAssay Description:STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB517JPubMed
LigandPNGBDBM20273((2S)-2-[(2S)-2-[(4-cyanophenyl)formamido]-3-[4-(ph...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
Yale University

LigandPNGBDBM20273((2S)-2-[(2S)-2-[(4-cyanophenyl)formamido]-3-[4-(ph...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed