Found 4 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50353444' TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto Mississauga
Curated by ChEMBL
University of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto Mississauga
Curated by ChEMBL
University of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 6.20E+3nMAssay Description:Displacement of fluorescein-labeled phosphotyrosine-peptide derived from the interleukin-6 receptor subunit gp130 from the STAT3 after 15 mins by flu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga
Curated by ChEMBL
University of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 6.54E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto Mississauga
Curated by ChEMBL
University of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair
