Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50382463'
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50382463(CHEMBL2023989)copy SMILEScopy InChI
Affinity DataKi:  7.90E+3nMAssay Description:Displacement of fluorescein-labeled phosphotyrosine-peptide derived from the interleukin-6 receptor subunit gp130 from the STAT3 after 15 mins by flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8SV2PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50382463(CHEMBL2023989)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+4nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1S6XPubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50382463(CHEMBL2023989)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+5nMAssay Description:Binding affinity to Stat3 (unknown origin) using hSIE as probe preincubated for 30 mins followed by hSIE addition by electrophoretic mobility shift a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1S6XPubMed