Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50396169'
LigandPNGBDBM50396169(CHEMBL1337170)copy SMILEScopy InChI
Affinity DataIC50: 670nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50396169(CHEMBL1337170)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of IFNgamma-stimulated GFP/FLAG-tagged STAT3 dimerization in human AD293 cells incubated for 6 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7SDKPubMed
LigandPNGBDBM50396169(CHEMBL1337170)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of STAT3 SH2 domain using 5-carboxyfluorescein-GY(PO3H2)LPQTV-NH2 as substrate preincubated for 60 mins prior to substrate addition by flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
LigandPNGBDBM50396169(CHEMBL1337170)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K9ZPubMed
LigandPNGBDBM50396169(CHEMBL1337170)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50396169(CHEMBL1337170)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50396169(CHEMBL1337170)copy SMILEScopy InChI
Affinity DataKd:  1.53E+3nMAssay Description:Binding affinity to His-tagged STAT3-SH2 domain (127 to 722 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP571BPubMed