Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Smoothened homolog' and Ligand = 'BDBM50277297'
TargetSmoothened homolog(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50277297((S)-6-methyl-N-(2-(thiophen-2-ylmethylamino)-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human Smo receptor expressed in CHO cells by [3H]Hh-Ag binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887ZNPubMed
TargetSmoothened homolog(Mus musculus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50277297((S)-6-methyl-N-(2-(thiophen-2-ylmethylamino)-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Antagonist activity at mouse Smo receptor expressed in CHO cells by [3H]Hh-Ag binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887ZNPubMed