Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Smoothened homolog' and Ligand = 'BDBM50352420'
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352420(CHEMBL1823865)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352420(CHEMBL1823865)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed