Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Smoothened homolog' and Ligand = 'BDBM50383034'
TargetSmoothened homolog(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50383034(CHEMBL2031084)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32BRPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50383034(CHEMBL2031084)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Antagonist activity at Smo receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7K6QPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50383034(CHEMBL2031084)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Antagonist activity at Smo receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32BRPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50383034(CHEMBL2031084)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32BRPubMed