Found 5 Enz. Inhib. hit(s) with Target = 'Smoothened homolog' and Ligand = 'BDBM50388722' 
Affinity DataIC50: 2.40nMAssay Description:Inhibition of SMO-mediated hedgehog signalling pathway in human HPEM cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Displacement of BODIPY-labeled cyclopamine from mouse SMO transfected in human HeLa cells by competition binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Displacement of BODIPY-labeled cyclopamine from human SMO transfected in human HeLa cells by competition binding assayMore data for this Ligand-Target Pair
