Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 1' and Ligand = 'BDBM176414'
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM176414(US9688710, 113 N-(2-methyl-1-(4-methylpiperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human HA-tagged SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake measured after 1 to 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24ZQ7PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM176414(US9688710, 113 N-(2-methyl-1-(4-methylpiperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154F7PUS Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM176414(US9688710, 113 N-(2-methyl-1-(4-methylpiperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154F7PUS Patent