Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50313364'
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50313364((2S,3R,4R,5S,6R)-2-(3-(4-ethylbenzyl)-4-methylphen...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6RBPPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50313364((2S,3R,4R,5S,6R)-2-(3-(4-ethylbenzyl)-4-methylphen...)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29X9TPubMed