Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 1' and Ligand = 'BDBM50104844'
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(BMS-284640 | CHEMBL51879 | N-[(1R,3R)-3-(2,3-Dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41QQ4PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(BMS-284640 | CHEMBL51879 | N-[(1R,3R)-3-(2,3-Dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC60MNPubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104844(BMS-284640 | CHEMBL51879 | N-[(1R,3R)-3-(2,3-Dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human NHE1 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56N68PubMed