Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 1' and Ligand = 'BDBM50396463'
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396463(CHEMBL2170611)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB5430PubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396463(CHEMBL2170611)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB5430PubMed