Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM381710'
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM381710(US10272079, Compound 67)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381710(US10272079, Compound 67)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent