Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM381826'
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))TBA
LigandPNGBDBM381826(US10272079, Compound 003)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)TBA
LigandPNGBDBM381826(US10272079, Compound 003)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)TBA
LigandPNGBDBM381826(US10272079, Compound 003)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))TBA
LigandPNGBDBM381826(US10272079, Compound 003)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:The ability of compounds to inhibit Rat NHE3-mediated Na+-dependent H+ antiport after application and washout was measured using a modification of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))TBA
LigandPNGBDBM381826(US10272079, Compound 003)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent