Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 10 subunit alpha' and Ligand = 'BDBM50330933'
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330933(CHEMBL1277514 | N-(3,5-Dimethylphenyl)-6-(4-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31KGPubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330933(CHEMBL1277514 | N-(3,5-Dimethylphenyl)-6-(4-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31KGPubMed
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330933(CHEMBL1277514 | N-(3,5-Dimethylphenyl)-6-(4-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31KGPubMed