Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 2 subunit alpha' and Ligand = 'BDBM50066068'
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50066068(CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+3nMAssay Description:Blockade of synaptosomal sodium channels, inhibition of [14C]-guanidinium ion flux into CHO cells expressing Type II sodium channelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q200022B
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066068(CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066068(CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed