Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 2 subunit alpha' and Ligand = 'BDBM50233224'
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50233224(CHEMBL4070670)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human Nav1.2 expressed in HEK293T cells assessed as inhibition of VTD-induced tail current by whole cell patch clamp method re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TC3PubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50233224(CHEMBL4070670)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human Nav1.2 expressed in HEK293T cells assessed as inhibition of VTD-induced sustained current by whole cell patch clamp meth...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TC3PubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50233224(CHEMBL4070670)copy SMILEScopy InChI
Affinity DataEC50:  120nMAssay Description:Inhibition of Nav1.2 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TC3PubMed