Found 5 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM371776' TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University of California at San Francisco
University of California at San Francisco
Affinity DataIC50: 0.5nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University of California at San Francisco
University of California at San Francisco
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University of California at San Francisco
University of California at San Francisco
Affinity DataIC50: 40nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as V1/2 of slow inactivation at 10 Hz frequency at -120 mV holding potential by single ...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University of California at San Francisco
University of California at San Francisco
Affinity DataIC50: 108nMAssay Description:Use-dependent inhibition of human Nav1.7 expressed in HEK293 cells at 25 pulse 10 Hz frequency at -120 mV holding potential by manual patch clamp ass...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University of California at San Francisco
University of California at San Francisco
Affinity DataIC50: 134nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as V1/2 of fast inactivation at 10 Hz frequency at -120 mV holding potential by single ...More data for this Ligand-Target Pair
