Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM50450593'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450593(CHEMBL4164272)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450593(CHEMBL4164272)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Nav1.7 in C57/BL6 mouse DRG neurons assessed as reduction in TTX sensitive sodium channel-mediated currents by whole cell manual patch ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed