Found 5 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent GABA transporter 1' and Ligand = 'BDBM50003634' TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-Universit£t M£nchen
Curated by ChEMBL
Ludwig-Maximilians-Universit£t M£nchen
Curated by ChEMBL
Affinity DataKi: 186nMAssay Description:Displacement of NO 711 from mouse GAT1 expressed in HEK293 cell membranes after 40 mins by LC-ESI-MS-MS-based MS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Compound was tested for its ability to inhibit uptake of [3H]- GABA by cloned human GAT-1 transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Mus musculus)
Ludwig Maximilians University at Munich
Curated by ChEMBL
Ludwig Maximilians University at Munich
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in HEK293 cells after 25 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Binding affinity to GAT1More data for this Ligand-Target Pair
