Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent GABA transporter 1' and Ligand = 'BDBM50426075'
TargetSodium- and chloride-dependent GABA transporter 1(Mus musculus)
Ludwig Maximilians University at Munich

Curated by ChEMBL
LigandPNGBDBM50426075(CHEMBL473104)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in HEK293 cells after 25 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ38HVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50426075(CHEMBL473104)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of GAT-1 in rat brain homogenate assessed as decrease in [3H]GABA uptake preincubated for 8 mins followed by [3H]GABA addition and measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50426075(CHEMBL473104)copy SMILEScopy InChI
Affinity DataIC50: 148nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2MJJPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50426075(CHEMBL473104)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of mouse GAT1 mediated [3]GABA uptake expressed in HEK293 cells after 3 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69MF4PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50426075(CHEMBL473104)copy SMILEScopy InChI
Affinity DataKd:  27nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD227RPubMed