Found 18 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent GABA transporter 1' and Ligand = 'BDBM90787' TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.59E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.59E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.65E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.65E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.66E+3nMAssay Description:H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.66E+3nMAssay Description:H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.77E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.77E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.79E+3nMAssay Description:H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compoundMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Mus musculus)
Ludwig Maximilians University at Munich
Curated by ChEMBL
Ludwig Maximilians University at Munich
Curated by ChEMBL
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in HEK293 cells after 25 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation
Curated by ChEMBL
Synaptic Pharmaceutical Corporation
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation
Curated by ChEMBL
Synaptic Pharmaceutical Corporation
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Budapest University of Technology and Economics
Curated by ChEMBL
Budapest University of Technology and Economics
Curated by ChEMBL
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of mouse GAT1 mediated [3]GABA uptake expressed in HEK293 cells after 3 mins by scintillation countingMore data for this Ligand-Target Pair
