Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent betaine transporter' and Ligand = 'BDBM50039246'
TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of mouse mGAT2 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0Q0RPubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 7.17E+4nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2RS1PubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 7.17E+4nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ891CPubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P849XXPubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of human BGT1 assessed as [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154JB8PubMed
TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse BGT1 mediated [3]GABA uptake expressed in HEK293 cells after 3 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69MF4PubMed