Found 4 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 1' and Ligand = 'BDBM50457701' TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Dart NeuroScience LLC
Curated by ChEMBL
Dart NeuroScience LLC
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human GlyT1c expressed in HEK293 cells assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation ...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Dart NeuroScience LLC
Curated by ChEMBL
Dart NeuroScience LLC
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Dart NeuroScience LLC
Curated by ChEMBL
Dart NeuroScience LLC
Curated by ChEMBL
Affinity DataIC50: 142nMAssay Description:Inhibition of human GlyT1 expressed in human HEK cells assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Dart NeuroScience LLC
Curated by ChEMBL
Dart NeuroScience LLC
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
