Found 3 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2' and Ligand = 'BDBM50256745' TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
The University of Texas at El Paso
Curated by ChEMBL
The University of Texas at El Paso
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
The University of Texas at El Paso
Curated by ChEMBL
The University of Texas at El Paso
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human GlyT-2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptake preincubated for 30 mins followed by 3H]-glycine ad...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
The University of Texas at El Paso
Curated by ChEMBL
The University of Texas at El Paso
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human GlyT2 expressed in FreeStyle 293-F suspension cells incubated for 30 mins before [3H]glycine addition and measured af...More data for this Ligand-Target Pair
