Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50010195'
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataKi:  0.960nMAssay Description:Displacement of [3H]GBR-12935 from dopamine transporter of rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0GXKPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataKi:  0.960nMAssay Description:In vitro binding affinity of compound for Dopamine transporter with [3H]- GBR-12935 as radioligand in corpus striatum tissue from rat forebrainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72HGQ
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:In vitro binding affinity towards dopamine transporter in rat striatal membranes by [3H]GBR-12395 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZJ5PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50NM0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix Inc.

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [3H]3-beta-(4-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to dopamine transporter of cynomolgus monkey striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC61V6PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 1.26nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4XGPPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix Inc.

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HXJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4XGPPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50NM0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix Inc.

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HXJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0TGBPubMed