Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50032537'
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6S69PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6S69PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  6.90nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibitory activity determined for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory activity on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed