Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50055019'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055019(5-Phenyl-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-o...)copy SMILEScopy InChI
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [125I]- RTI-55 from Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC90R8PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055019(5-Phenyl-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Ability to displace [3H]WIN-35428 from Dopamine Transporter of rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC90R8PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055019(5-Phenyl-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of [3H]-WIN- 35,428 binding to the dopamine transporter in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5FSRPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055019(5-Phenyl-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z43R6PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055019(5-Phenyl-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 124nMAssay Description:Inhibition of [3H]-dopamine uptake at the dopamine transporter in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5FSRPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055019(5-Phenyl-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of dopamine uptake in HEK cells expressing human dopamine transporter (hDAT)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC90R8PubMed