Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50084716'
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084716((4-Hydroxy-1-methyl-4-p-tolyl-piperidin-3-yl)-p-to...)copy SMILEScopy InChI
Affinity DataKi:  360nMAssay Description:Inhibition of [3H]-DA Uptake at Dopamine transporter in rat cortex was measured by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7P39PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084716((4-Hydroxy-1-methyl-4-p-tolyl-piperidin-3-yl)-p-to...)copy SMILEScopy InChI
Affinity DataKi:  492nMAssay Description:Binding Affinity to cocaine site of Dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol .More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7P39PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084716((4-Hydroxy-1-methyl-4-p-tolyl-piperidin-3-yl)-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Antagonism of cocaine''s inhibition of [3H]-DA uptake at the dose of 50 nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7P39PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084716((4-Hydroxy-1-methyl-4-p-tolyl-piperidin-3-yl)-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 717nMAssay Description:Antagonism of cocaine''s inhibition of [3H]-DA uptake at the dose of 200 nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7P39PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084716((4-Hydroxy-1-methyl-4-p-tolyl-piperidin-3-yl)-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+3nMAssay Description:Antagonism of cocaine''s inhibition of [3H]-DA uptake at the dose of 500 nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7P39PubMed