Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50118294'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)copy SMILEScopy InChI
Affinity DataKi:  2.01nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VF3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VF3PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program/NIH

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z43R6PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program/NIH

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 37.3nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VF3PubMed