Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50149940'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human DA transporter assessed as reduction in [3H]-DA reuptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N5444PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent