Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50183656'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50183656((R)-1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95PHPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50183656((R)-1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of DAT (unknown origin) assessed as dopamine reuptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270F0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50183656((R)-1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of dopamine reuptake at human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4H0CPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50183656((R)-1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95PHPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50183656((R)-1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells assessed as decrease in [3H]-dopamine reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QTKPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50183656((R)-1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of DAT (unknown origin) assessed as dopamine reuptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270F0PubMed