Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50243895'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataKi:  251nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29886TFPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of dopamine uptake at human cloned DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26974G5PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Binding affinity to DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7K8MPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 93.8nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RQ7PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26974G5PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 394nMAssay Description:Inhibition of DA reuptake at human DAT expressed in HEK293 cells after 15 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MHHPubMed