Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM22416'
TargetSodium-dependent noradrenaline transporter(MOUSE)
McNeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Tested in vitro for norepinephrine (NE) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27S7PB4PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic Jacksonville

Curated by PDSP Ki Database
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  40nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H3DPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic Jacksonville

Curated by PDSP Ki Database
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  45nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0CPWPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic Jacksonville

Curated by PDSP Ki Database
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  85nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4TMXPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic Jacksonville

Curated by PDSP Ki Database
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Binding inhibition towards human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96DNPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic Jacksonville

Curated by PDSP Ki Database
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  145nMAssay Description:NET: This protocol was designed to measure inhibition of uptake by the human norepinephrine transporter. The reagents were human NET (HEK293F) cells,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5WBRUS PatentDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic Jacksonville

Curated by PDSP Ki Database
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  156nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0CPWPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic Jacksonville

Curated by PDSP Ki Database
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  328nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4TMXPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic Jacksonville

Curated by PDSP Ki Database
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S183C9PubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic Jacksonville

Curated by PDSP Ki Database
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKd:  40nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76D26PubMedDrugBank