Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50010859'
TargetSodium-dependent noradrenaline transporter(MOUSE)
McNeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Tested in vitro for norepinephrine (NE) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27S7PB4PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Binding affinity towards Norepinephrine transporter using [3H]-nisoxitine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5ZK3PubMedDrugBank
TargetSodium-dependent noradrenaline transporter(MOUSE)
McNeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Binding affinity to Norepinephrine transporter using [3H]-nisoxatine as radioligand in stably transfected NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H994F8PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4TMXPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataKi:  37nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H3DPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(BOVINE)
The University of Queensland

Curated by PDSP Ki Database
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataKi:  93.6nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6HNFPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataKi:  98nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W98PubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataKi:  118nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6HNFPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataKi:  142nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4TMXPubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMedDrugBank