Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50084717'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  182nMAssay Description:Inhibition of [3H]DA uptake in human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC83PBPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Inhibition of reuptake of [3H]-NE (20 nM) by norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6DXDPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  264nMAssay Description:Compound was evaluated for inhibition of [3H]NE uptake in HEK-hNET cells expressing Human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4C8XPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96F3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  830nMAssay Description:Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HMBPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  887nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC83PBPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.12E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.12E+3nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.74E+3nMAssay Description:Compound was evaluated for binding affinity using [125I]RTI-55 as a radioligand in HEK-hNET cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4C8XPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.77E+3nMAssay Description:Binding affinity at the norepinephrine transporter was measured using [125I]RTI-55 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MW0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PPJPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.94E+3nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC90R8PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.99E+3nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GTJPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.99E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2611186PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.99E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.99E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28053DMPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  1.99E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  2.15E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9CKBPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  2.38E+3nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZC2PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity against norepinephrine cloned human transporter using 40-80 pM [125I]RTIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6DXDPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96F3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]- NE uptake in HEK cells expressing norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PPJPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]NE reuptake by human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MW0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 232nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZC2PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 233nMAssay Description:Inhibition of NE uptake in HEK cells expressing human noradrenaline transporter (hNET)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC90R8PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 378nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9CKBPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 385nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HMBPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 462nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319WP1PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 835nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of rat NET-mediated norepinephrine uptake in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2HM6PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MZZPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 2.99E+3nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319WP1PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KJXPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X4BPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of [3H]nisoxetine from human NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28053DMPubMed