Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50124566'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity of the compound was determined against human norepinephrin transporter in human embryonic kidney cell line by using [3H]-ni...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GG7PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z036RSPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]Nisoxetine uptake in human noradrenaline transporter transfected HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125TH5PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Invitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66K4VPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4XQTPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S183C9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V1CPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99VSPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5V9WPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]NA reuptake at NA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ916HPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99608PubMed