Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50188098'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50188098((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09X4PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50188098((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]NA reuptake at NA transporter in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ916HPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50188098((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]NA uptake at human NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2WBXPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50188098((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T44PubMed