Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50243500'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243500((-)-1-[(1S)-1-(3-Chlorophenyl)-2-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243500((-)-1-[(1S)-1-(3-Chlorophenyl)-2-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243500((-)-1-[(1S)-1-(3-Chlorophenyl)-2-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human NET transfected in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RQVPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243500((-)-1-[(1S)-1-(3-Chlorophenyl)-2-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human NET transfected in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RQVPubMed