Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM22166'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29WMFPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9GT3PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKi:  3.10nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X928VCPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3CWQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant SERT expressed in african gree...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Binding affinity to SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P92BDPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKi:  66.3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3CWQPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKd:  2.82nMAssay Description:Displacement of [125I]beta-CIT from human SERT in human platelet membrane in presence of 5 uM ibogaineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125SG9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKd:  0.880nMAssay Description:Displacement of [125I]beta-CIT from human SERT in human platelet plasma membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125SG9PubMed